Dr. Hector Fabricio Espinosa Ortega

Especialidad: Epidemiología Clínica, Solna (KEP)
País: Suecia

Educación

01/2000 – 01/2006 Medical doctor (MD)
Universidad: Universidad Anáhuac (Ciudad de México)
03/2007 – 03/2011 Especialidad en Medicina Interna.
Universidad: Universidad Nacional Autónoma de México (Ciudad de México)
03/2011 – 03/2013 Especialidad en Reumatología
Universidad: Universidad Nacional Autónoma de México (Ciudad de México)
09/2020 – 02/2023 Fellowship en Reumatología, Hospital Universitario Karolinska
04/2023 Doctor en Ciencias Médicas (PhD), Karolinska Institutet

Experiencia Profesional

03/2013 – 05/2017 Médico Adjunto al Servicio de Reumatología,
Hospital Central Sur Alta Especialidad, Ciudad de México.
02/2023 Médico Adjunto al Servicio de Reumatología,
Hospital Universitario Karolinska

Producción Científica

Accepted abstractt – Poster
• 35th Scandinavian Congress of Rheumatology 2014 Stockholm. “Quantitative T cell profile in peripheral
blood from idiopathic inflammatory myositis patients” Scand J Rheumatol 2014;43:Suppl127.
• ACR Annual meeting 2015 San Francisco CA, US. “Impact of Osteoarthritis of the Hand on Disease
Activity Scores and Health Status in patients with Rheumatoid Arthritis” Arthritis Rheumatol.
2015;67:Suppl10.
• EULAR Annual Meeting 2015 Rom, Italien. “Systematic review and meta-analysis of the efficacy and
safety of leflunomide or methotrexate in the treatment of rheumatoid arthritis” Ann Rheum Dis
2015;74:Suppl 2 739-740.
“Predictability to Achieve Low Activity and/or Remission with Leflunomide use in Patients with Rheumatoid
Arthritis” Ann Rheum Dis 2015;74:Suppl 2:261.
• EULAR Annual Meeting, London, England, 2016. “Benchmarking disability with the HAQ-DI. A new
normogram in a Latinamerican non-rheumatic population”. Ann Rheum Dis 2016;75:Suppl 2:960-1.
• EULAR Annual Meeting, Amsterdam, NE, 2018. “Prognostic markers for response according to the new
acr/eular 2016 response criteria for idiopathic inflammatory myositis”. Ann Rheum Dis 2018;77:Suppl
2:849-50.
• 37th Scandinavian Congress of Rheumatology, Helsinki, Finland, 2018. “Elevated erythrocyte
sedimentation rate at time of diagnosis is associated with high mortality in patients with idiopathic
inflammatory myopathies: a register-based study”. Scand J Rheumatol 2018;47:Suppl 129:52
• EULAR Annual Meeting, Madrid, Spanien, 2019. “Skeletal troponin i a possible novel biomarker for
management of patients with idiopathic inflammatory myopathies”. Ann Rheum Dis;2019:79:Suppl 2:445.
• Global Conference on Myositis, Berlin, Tyskland, 2019. “Comparison of autoantibody specificities tested
by a line blot assay and immunoprecipitation-based algorithm in patients with idiopathic inflammatory
myopathies”. BMC Rheumatology 2019;3:Suppl 1:P3
• EULAR Annual meeting, Frankfurt, Tyskland, 2020. “Autoantibodies can partly predict severity of damage
but not extent in patients with idiopathic inflammatory myositis”. Ann Rheum Dis 2020;79:Suppl 1:398-99.
• 38th Scandinavian Congress of Rheumatology, Ålesund, Norge, 2021. “Myositis-specific and myositis
associated autoantibodies predict trajectories of damage over time in idiopathic inflammatory
myopathies.” Scand J Rheumatol 2021;50:Suppl 130:49-50.
Presentación Oral
• 5th Annual workshop for myositis, Praga, República Checa 2018. “Autoantibodies as predictors of
outcomes in patients with Idiopathic inflammatory myopathies”.
• American CR Annual meeting 2022, Filadelfia, EUA. “Damage and autoantibodies in patients with
idiopathic inflammatory myopathies”.
Ponente Invitado
• 16th Dresden Symposium on Autoantibodies, Dresden, Alemania septiembre 2023. “Differentiation of
idiopathic inflammatory myopathies by increasing number of myositis autoantibodies”.
• Congreso Mexicano de Reumatología, febrero 2025. “Fenotipos serológicos en miopatías inflamatorias
idiopáticas”.

Revisor para revistas médicas

• Clinical Rheumatology. Manuscritos revisados: 23
• The Journal of Rheumatology. Manuscritos revisados: 1
Diez publicaciones más relevantes
1) Espinosa-Ortega F, Lodin K, Dastmalchi M, Venkovsky J, Diederichsen LP, Shinjo SK, Danieli MG, Selva
O’Callaghan A, De Visser M, Griger Z, Ceribelli A, Gómez-Martin D, Andersson H, Vázquez-Del Mercado M,
Chinoy H, Lilleker JB, New P, Krogh NS, Lundberg IE, Alexanderson H, MYONET Registry Study Group.
Autoantibodies and damage in patients with idiopathic inflammatory myopathies: A longitudinal
multicenter study from the MYONET international network. Semin Arthritis Rheum 2024; 68:152529
2) Espinosa-Ortega F, Holmqvist M, Alexanderson H, Storfors H, Mimori T, Lundberg IE, Rönnelid J.
Comparison of autoantibody specificities tested by a line blot assay and immunoprecipitation-based
algorithm in patients with idiopathic inflammatory myopathies. Ann Rheum Dis 2019;78:858-860
3) Lodin K, Espinosa-Ortega F; Dastmalchi M; Vencovsky J; Andersson H; Chinoy H; Lilleker JB; Shinjo S;
Maurer B; Griger Z; Ceribelli A; Torres-Ruiz J; Vázquez Del Mercado M; Leonard D, Alexanderson H,
Lundberg IE. Patient global assessment and inflammatory markers in patients with idiopathic inflammatory
myopathies – a longitudinal study. Semin Arthritis Rheum 2024;24:65:152379.
4) Espinosa-Ortega F, Holmqvist M, Dastmalchi M, Lundberg IE, Alexanderson H. Factors associated with
treatment response in patients with idiopathic inflammatory myopathies. A registry-based study. Arthritis
Care Res 2022, Mar;74(3):468-77.
5) Andreasson KM, Espinosa-Ortega F, Sandlund H, Alexanderson H. Self-reported physical activity and
fatigue and its asscciations to anxiety and depression in adult patients with idiopathic inflammatory
myopathies: a MIHRA psychological impact and MIHRA exercise and rehabilitation scientific wrokign
groups collaboration. Clin Exp Rheumatol 2024 Sep 10. Epub ahead of print
6) Bamberg K, Mehtälä L, Arola O, Laitinen S, Nordling P, Strandberg M, Strandberg N, Paltta J, Mali M,
Espinosa-Ortega F, Pirilä L, Lundberg IE, Savukoski T, Pettersson K. Evaluation of a new skeletal troponin I
assay in patients with idiopathic inflammatory myopathies. J Appl Lab Med 2020;5(2):320-331.
7) Lodin K, Espinosa-Ortega F, Lundberg IE, Alexanderson H. Improving physiological, physical, and
psychological health outcome in IIM. J Inflamm Res 2024, jun 5:17:3563-85.
8) Espinosa-Ortega HF, Moreno-Ramirez M, Alexanderson H. Novel insights of disability assessment in
adult myositis. Curr Opin Rheumatol 2017;29:591-7.
9) Espinosa-Ortega F, Gómez-Martin D, Santana-De Anda, K et al. Quantitative T cell subsets profile in
peripheral blood from patients with idiopathic inflammatory myopathies: tilting the balance towards
proinflammatory and pro-apoptotic subsets. Clin Exp Immunol 2015;179:520-8.
10) Ruiz-Medrano E, Espinosa-Ortega F, Arce-Salinas CA. The effect of concomitant hand osteoarthritis
on pain and disease activity in patients with rheumatoid arthritis. Clin Rheumatol 2019;38:10: 2709-16.